How do most body cells interact with interstitial fluid?

Most body cells generally interact directly with interstitial fluid, which is the fluid that fills the spaces between cells in tissues. This fluid plays a crucial role in facilitating nutrient exchange and waste removal between blood vessels and the cells. The interstitial fluid acts as a medium through which essential substances, such as oxygen and nutrients, diffuse from the blood into the cells, and metabolic waste products move from the cells back into the blood for elimination.

This close interaction allows cells to maintain homeostasis and optimal functioning, as they constantly receive the necessary materials and dispose of waste products. The dynamic nature of this interaction is vital for cellular health and overall tissue function. It underscores the importance of interstitial fluid as a critical component of the extracellular environment that supports cell viability and activity.