Which of the following statements about the Na+-K+ ATPase pump is false?

Enhance your knowledge for the General Principles of Physiology Exam. Utilize flashcards and multiple-choice questions, each with detailed explanations. Prepare effectively for your test!

The Na+-K+ ATPase pump is a vital membrane protein that maintains the electrochemical gradient of cells by actively transporting sodium (Na+) and potassium (K+) ions across the plasma membrane. The pump operates by moving three Na+ ions out of the cell for every two K+ ions it imports into the cell. This creates a net loss of one positive charge from the cell, which is crucial for functions such as generating action potentials in nerve and muscle cells.

The correct interpretation highlights that the Na+-K+ ATPase does not transport Na+ and K+ in a 1:1 ratio; instead, it transports them in a 3:2 ratio. This key aspect is fundamental to understanding how the pump contributes to establishing and maintaining the resting membrane potential, as well as its role in regulating cell volume and other physiological processes.

The other statements are accurate reflectively describing the pump's operation. It indeed transports Na+ out of the cell and K+ into the cell, which is essential for maintaining cellular homeostasis. Additionally, the pump is an ATPase which means it can bind to ATP and hydrolyze it to power the transport of ions, an activity that requires metabolic energy.

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